三、主要科研工作与成绩 1.主持国家级科研项目6项 国家自然科学基金面上项目《Nrp1抑制2型固有淋巴细胞的活化在脓毒症心肌损伤中的作用机制研究 》(项目批准号:82272228 ,52万,2023-2026); 国家自然科学基金面上项目《2型固有淋巴细胞促进心梗后心肌纤维化的作用及其活化的调控机制研究》(项目批准号:82072199,55万,2021-2024); 国家自然科学基金面上项目《双靶向纳米化miRNA-204治疗心肌缺血再灌注损伤的机制研究》(项目批准号:81470390,73万,2015-2018); 国家自然科学基金青年-面上连续项目《miRNA-204和miRNA-1对缺血再灌注损伤后的心肌自噬的调控机制研究》(项目批准号:81270003, 70万,2013-2016); 国家自然科学基金青年项目《miRNA-1和miRNA-133在缺血后处理的心肌保护机制中的调控作用研究》(项目批准号:30901470,19万,2010-2012); 国家教育部留学回国人员科研启动基金《自噬在硫化氢心肌保护中的作用及miRNA的调控作用》(项目批准号:教外司留〔2013〕1792,3万,2014-2016)。
2.通讯作者发表中科院一区学术论文 [1] Neuropilin-1 mediates lung tissue-specific control of ILC2s function in type 2 immunity. Nature Immunology, 2022;23(2): 238-250.(IF=31.25,中科院一区) [2] Reporter molecules embedded Au@Ag core-shell nanospheres as SERS nanotags for cardiac troponin I detection. BIOSENSORS BASEL.2022; 12:1108. (IF=5.74, JCR一区) [3] Thrombus-Specific/Responsive Biomimetic Nanomedicine for Spatiotemporal Thrombolysis and Alleviation of Myocardial Ischemia/Reperfusion Injury. J Nanobiotechnol. 2022; 20:531. (IF = 9.43, 中科院一区) [4] Lipocalin-2 Participates in Sepsis-Induced Myocardial Injury by Mediating Lipid Accumulation and Mitochondrial Dysfunction. Front Cardiovasc Med. 2022;9:1009726 (IF=5.85, JCR一区) [5] A Novel Photoelectrochemical Sensor Based on SiNWs@PDA for Efficient Detection of Myocardial Infarction.Biomaterials Science,2022;10(16):4627-4634.(IF=7.59,JCR一区) [6] Polydopamine stabilizes silver nanoparticles as a SERS substrate for efficient detection of myocardial infarction. Nanoscale, 2022;14:6212-6219.(IF=8.31,中科院一区) [7] Dual-emissive polyaniline derived lotus-pod nano-hybrids for ultrasensitive and highly selective flfluorescent recognition towards aniline. Carbon, 2022;192;265-276.(IF=11.31,中科院一区) [8] Engineered Biomimetic Nanoplatform Protects the Myocardium Against Ischemia/Reperfusion Injury by Inhibiting Pyroptosis. ACS Applied Material & Interfaces, 2021, 13:33756-33766. (IF=10.38, 中科院一区) 3.专著专利 专著3篇,专利16项 |