赵改平
职称:副教授
导师资格:硕导
学科专业:生物医学工程
电话:无
邮箱:zgp_06@126.com
个人简介
工作经历
教育经历
研究方向
主要科研项目
代表性专利
代表性论文

2007/07 – 至今, 上海理工大学, 健康科学与工程学院, 副教授(硕导)

2007/07 – 至今, 上海理工大学, 健康科学与工程学院, 副教授(硕导)

2004/09 – 2007/07, 复旦大学, 力学与工程科学系, 博士

2001/09 – 2004/07, 内蒙古民族大学, 理论物理, 硕士

1996/09 – 2000/07, 内蒙古民族大学, 物理系, 本科

1. 骨肌系统生物力学和植介入医疗器械的研发设计

2. 肿瘤血管生成、血液动力学和药物输运的生物力学研究

3. 眼组织的生物力学研究(OK镜研发)

【主持】

[1] 国防科工局,工业基础能力提升:基于机器学习XXX(子课题负责人), 2025/01 – 2027/12.

[2] 国家自然科学基金: 乳腺癌结合抗血管生成和放疗联合治疗的数值模拟和动物实验研究(11502146), 2016/01 – 2018/12.

[3] 上海市自然科学基金: 靶向VEGF药物联合放疗治疗乳腺癌增敏与抑制机理的生物力学研究(15ZR1429600), 2015/01 – 2017/12.

[4] 微创视神医疗科技有限公司: 眼科生物力学研究分析(H2021308054), 2021/9 – 2022/09.

[5] 中国人民解放军海军军医大学第一附属医院项目,XXX固定装置的研发, 2023/01 – 2025/12.

[6] 中船704研究所,旋转类流体设备涡致流噪声机理及特性分析(H2023312096), 2023/10 – 2025/10.

[7] 中国人民解放军海军军医大学第二附属医院: 人脊柱标本内固定生物力学检测(H2022312052), 2022/11 – 2023/02.

[8] 广东省微创手术器械设计与精密制造重点实验室项目: 腰椎微创融合系统的结构设计与生物力学研究(Z2023312049), 2022/01 – 2024/12. 

[9] 罗莱生活科技股份有限公司: 人体工学枕头骨架结构设计及应用研究(H2022312007), 2022/03 – 2023/06.

[10] 上海市药品和医疗器械不良反应监测中心: 药物洗脱冠状动脉支架不良事件信息采集分析(H2024312083), 2024/08 – 2024/12.

[11] 兰胜医疗科技(上海)有限公司: 眼科生物力学分析研究(H2025312049), 2025/06 – 2026/06.

[12] 上海饭芒科技有限公司: 背包骨架结构设计和有限元分析研究(H2023312096), 2023/10 – 2024/10.

[13] 上海市第六人民医院合作医工交叉项目: 新型胫骨近端联合截骨术(CPTO)专用截骨矫形钢板的设计和研发, 2022/09 – 2024/10.

[14] 上海交通大学附属瑞金医院合作医工交叉项目: 具有形状记忆效应和可控降解的颈动脉支架研制, 2023/09 – 2025/10.

[15] 复旦大学附属中山医院合作医工交叉项目: 肿瘤消融术中头端增强可视性微波消融针设计和研发, 2022/03 – 2024/03.

[16] 同济大学附属杨浦区中心医院: 步态周期下单髁置换术的有限元研究(H2025312016), 2025/01 – 2026/12.

【参与】

[1]国防科工局,工业基础能力提升:XXX融合设计, 2023/01 – 2026/12.

【授权专利】

[1] 一种胫骨近端联合截骨术专用内固定装置,国家发明专利,中国,ZL 202111667112.9,2025年7月11日(转让)

[2] 同种异体骨切割设备的夹持装置,国家发明专利,中国,ZL 201310589874 ,受理时间:2016年8月17日(转让)

[3] 一种用于手术器械扭矩实时可视化的力矩性能测试装置,国家发明专利,中国,ZL 202110469062.7,2022年12月16日

[4] 不规则脊柱生物力学实验固定装置,国家发明专利,中国,ZL 2019113925111,2022年03月22日 

[5] 骨植入材料的软骨旋转剔除设备系统,国家发明专利,中国,ZL CN201810777923.6,2018年07月16日

[6] 一种三维有限元网格精准定位放射治疗系统,国家发明专利,中国,ZL 202111357090.6,2023年11月23日

[7] 一种医用活检包埋盒包装系统,国家发明专利,中国,ZL 201811422574.2,2021年02月12日 

[8] 一种负载自适应气动平衡呆装置,国家发明专利,中国,ZL 201611050412.1,2018年06月22日

[9] 臀要结合的康复理疗装置,国家发明专利,中国,ZL  CN201810289672,2018年07月16日

[10] 3D打印的颈椎全脊椎切除术可植入假体装置,国家发明专利,中国,ZL CN201710022331,2019年12月06日

【学术专著】

[1] Aslanidis, Theodoros, Olena Lutsenko,Yoko Kato,Branislav Kolarovszk,Gaiping zhao. Highlights on Hemodynamics. BoD–Books on Demand, Intechopen,2018.

【代表性论文】

[1] Biomechanical Analysis of Proximal Junctional Kyphosis in Osteoporotic Thoracolumbar Fusion With Different Reinforcement Strategies. International Journal for Numerical Methods in Biomedical Engineering, 2025, 41(6): e70056.

[2] Mechanical characteristics of braided composite stents for carotid artery stenosis using finite element method.Computer Methods in Biomechanics and Biomedical Engineering,2025, 1-9.

[3] Biomechanical investigation of a customized interspinous spacer system in the treatment of degenerative disc diseases: A finite element analysis. Clinical Biomechanics, 2024,110: 106270.

[4] Regulatory T cell-associated gene signature correlates with prognostic risk and immune infiltration in patients with breast cancer. Translational Cancer Research, 2024, 13(12): 6766.

[5] Identification of disulfidptosis-related clusters and construction of a disulfidptosis-related gene prognostic signature in triple-negative breast cancer. Heliyon, 2024, 10(12).

[6] Biomechanical study of cornea response under orthokeratology lens therapy: A finite element analysis [J]. Int J Numer Method Biomed Eng, 2023,39(10):: e3691.

[7] Biomechanical effects of osteoporosis severity on the occurrence of proximal junctional kyphosis following long-segment posterior thoracolumbar fusion. Clinical Biomechanics, 2023,110:106132.

[8] Numerical sensitivity study on nucleation bulk tension factor of non-equilibrium condensation model[J]. Journal of Mechanical Science and Technology, 2023: 1-9.

[9] Biomechanical evaluation of combined proximal tibial osteotomy for varus knee osteoarthritis implanted novel designed plate system: finite element analysis. Injury. 2022, 53(7):2416-2423.

[10] A biomechanical study of ligament tethers strengthening for the prevention of proximal junctional kyphosis after posterior long-segment spinal fusion. Clinical biomechanics, 2022, 94: 105621. 

[11] Biomechanical investigation of intra-articular cage and cantilever technique in the treatment of congenital basilar invagination combined with atlantoaxial dislocation: A finite element analysis. Medical& Biological Engineering& Computing,2022, DOI10.1007/s11517-022-02596-y.

[12] Biomechanical analysis of a customized lumbar interspinous spacer based on transfacetopedicular screw fixation: A finite element study[J]. Medical Engineering & Physics. 2022, 107:103850. 

[13] The design of a novel arthroscopy shaver. Science reports.2022,12(1): 1-9.

[14] A biomechanical study of proximal junctional kyphosis after posterior long segment fusion with vertebral body augmentation. Clinical Biomechanics, 2021, 87: 105415.

[15] A ten N6-methyladenosine- related long non-coding RNAs signature predicts prognosis of triple-negative breast cancer. Journal of Clinical Laboratory analysis, 2021, 36(6): e23779.

[16] Assessment of arthroscopic shavers: a comparison test of resection performance and quality. Journal of Orthopaedic Surgery and Research, 2020,15(1):62.

[17] Three-dimensional finite element analysis of the effects of ligaments on human sacroiliac joint and pelvis in two different positions. ASME. J Biomech Eng., 2020, 142(8):081007.

[18] Advances in toxicity risk analysis and effective treatments for targeted antiangiogenic drugs. International Journal of Clinical and Experimental Medicine, 2019,12(10): 12020-12027.

[19] The diagnosis and treatment of knee osteoarthritis: a literature review. International Journal of Clinical and Experimental Medicine. 2019,12(5):4589-4599.

[20] Experimental investigation on noise emissions of an airfoil with non-flat plate trailing edge serrations. Journal of Mechanical Science and Technology, 2019,33(7): 3069-3074.

[21] Molecular mechanism of activated T cells in breast cancer. Oncotargets and Therapy,2018,11:5015-5024. 

[22] Effect of Guide Vanes on Flow and Vibroacoustic in an Axial-Flow Pump. Mathematical Problems in Engineering, 2018, 3095890.

[23] Three-dimensional model of metastatic tumor angiogenesis in response to anti-angiogenic factor angiostatin[J]. Journal of Mechanics in Medicine and Biology, 2017, 10:1750094.

[24] 3D numerical simulation of effect of antiangiogenic factor angiostatin on blood flow and interstitial fluid pressure in the metastatic tumor,Molecular and Cellular Biomechanics, 2017,14(1):49-62.